Does the Stem Cell Oversight Committee need to review my research proposal?
The Stem Cell Oversight Committee (SCOC) must review all research proposals involving human pluripotent and human totipotent stem cells that have been derived from an embryonic source, and/or will be transferred into humans or non-human animals, conducted under the auspices of institutions eligible to receive funding directly from an Agency. SCOC only reviews research proposals for which funding has already been secured.
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My research only involves in vitro use of human induced pluripotent stem cells
SCOC review is not required for research involving only in vitro use of human induced pluripotent stem cells. Verify with your institution’s Research Ethics Board if their review is required.
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My research involves only in vitro use of human pluripotent or human totipotent stem cells that have been derived from an embryonic source
For research involving in vitro use of human pluripotent or human totipotent stem cells that have been derived from an embryonic source, both SCOC and your institution’s Research Ethics Board must review.
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My research only involves the use of human induced pluripotent stem cells in teratoma assays in non-human animals, where the animals will not be used for reproductive purposes
SCOC review is not required, but you must notify SCOC of this research in writing.
Review from your institution’s Animal Care Committee is required.
Verify with your institution’s Research Ethics Board if their review is required.
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My research involves engraftment or transfer of human pluripotent or human totipotent stem cells, or cells derived from those cells, in non-human animals
For research involving engraftment or transfer of human pluripotent or human totipotent stem cells, or cells derived from those cells, in non-human animals, review is required by SCOC, your institution’s Research Ethics Board, and your institution’s Animal Care Committee.
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My research involves engraftment or transfer of human pluripotent or human totipotent stem cells, or cells derived from those cells, in humans
For research involving engraftment or transfer of human pluripotent or human totipotent stem cells, or cells derived from those cells, in humans, review is required by SCOC, your institution’s Research Ethics Board, and Health Canada.
Long description
Does the Stem Cell Oversight Committee (SCOC) need to review my research proposal?
SCOC only reviews proposals for which funding has been secured
| If the research involves | SCOC | Health Canada | Your institution’s Research Ethics Board | Your institution’s Animal Care Committee |
|---|---|---|---|---|
| only in vitro use of human induced pluripotent stem cells | Verify with your institution’s Research Ethics Board if their review is required | |||
| in vitro use of human pluripotent or human totipotent stem cells that have been derived from an embryonic source | ✓Review required | ✓Review required | ||
| only the use of human induced pluripotent stem cells in teratoma assays in non-human animals, where the animals will not be used for reproductive purposes | SCOC review not required – notify SCOC in writing | Verify with your institution’s Research Ethics Board if their review is required | ✓Review required | |
| engraftment or transfer of human pluripotent or human totipotent stem cells, or cells derived from those cells, in non-human animals | ✓Review required | ✓Review required | ✓Review required | |
| engraftment or transfer of human pluripotent or human totipotent stem cells, or cells derived from those cells, in humans | ✓Review required | ✓Review required | ✓Review required | |
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(✓): Review required. |
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If your research proposal meets the requirements for SCOC review, please submit a completed application form to StemCell-Cellulesouche@cihr-irsc.gc.ca
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